Oral-B iO vs Pro Replacement Heads

Oral-B iO heads fit iO handles; standard rotating Pro/Vitality heads use another connection. Do not interchange them.

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Exact pair comparison

Exact pair records; an absent pair is Unknown
Handle	Head	Catalog result
Oral-B iO Series 6	Oral-B iO Gentle Care	Confirmed fit
Oral-B iO Series 6	Oral-B CrossAction	Confirmed not fit
Oral-B Pro 1000	Oral-B iO Gentle Care	Confirmed not fit
Oral-B Pro 1000	Oral-B CrossAction	Confirmed fit

Why this matters

Marketing names often cover multiple generations. The connector, model code and manufacturer fit list are the reliable purchase checks. A head that looks similar may fail to attach, and smart features need their own support check.

What to do next

Read the code printed on the handle.
Search that code in the model finder.
Open the exact head family and compare the retail pack part number.

Search your exact handle →

Search the recorded replacement on Amazon

These are search-result links, not verified Amazon product listings. Price, stock and seller authenticity are not checked.

Oral-B iO Gentle Care

This head family has a documented fit in the BrushMatch catalog. Amazon search results may contain other products; confirm the exact head and your handle before ordering.

(paid link)

Search this head on Amazon

Oral-B CrossAction

This head family has a documented fit in the BrushMatch catalog. Amazon search results may contain other products; confirm the exact head and your handle before ordering.

(paid link)

Search this head on Amazon

Sources and scope

Oral-B replacement-head fit guide · manufacturer; web search excerpt; retrieved 2026-10-30
Which iO is right for you? · manufacturer; web search excerpt; retrieved 2026-10-30